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Intervention Research and Evidence-Based Quality Improvement: Designing, Conducting, Analyzing, and Funding 2ed

by Bernadette Mazurek Melnyk and Dianne Morrison-Beedy Springer Publishing Company
Pub Date:
Pbk 480 pages
AU$172.00 NZ$177.39
Product Status: Out of stock. Not available to order.
& Academics:
Written for researchers, clinicians and doctoral students, the newly revised edition of this comprehensive reference continues to deliver the essentials of intervention research with added content on evidence-based quality improvement, a must for improving healthcare quality, safety and population health outcomes. Although typically it takes years for research-based interventions to make their way to real world clinical settings, this “prolonged time for translation ” frustrates researchers and their interprofessional teams. This second edition now delves even deeper into key strategies for rapidly moving research-based interventions into real world settings in the form of evidence-based quality improvement as well as the challenges of working in an increasingly diverse professional research environment.


Intervention Research and Evidence-Based Quality Improvement, Second Edition begins at the pilot study phase for intervention research and highlights every step of the way through to full-scale randomized controlled trials. Written in user-friendly format, content covers designing, conducting, analyzing, and funding intervention studies that improve healthcare quality and people's health outcomes. Chapters cover writing grant applications and show examples of actual applications that have been funded by NIH and other organizations. These real-life samples are available online, alongside additional progress reports and final reports. Real-world examples of evidence-based quality improvement projects that have improved outcomes also are highlighted in this second edition.


New to the Second Edition:


  • Describes evidence-based quality improvement and specific steps in conducting EBQI projects, which are essential for enhancing healthcare quality, safety and costs along with enhancing population health outcomes.

  • Emphasizes the importance of interprofessional teams

  • Focuses on using research-based interventions in real-world settings

  • Six new chapters

  • o Generating Versus Using Evidence to Guide Best Practice


  • o Setting the Stage for Intervention Research and Evidence-based Quality Improvement


  • o Evidence-based Quality Improvement


  • o Translational Research: Why and How


  • o Factors Influencing Successful Uptake of Evidence-Based Interventions in Clinical Practice


  • o Using Social Media to Enhance Uptake of Research-Based Interventions into Real World Clinical Settings

Key Features:


  • Provides a practical, comprehensive resource for designing, conducting, analyzing, and funding intervention studies

  • Outlines the specific steps in designing, conducting and evaluating outcomes of evidence-based quality improvement projects

  • Includes examples of funding research grants, progress reports, and final reports

  • Serves as a core text for students in doctoral nursing and other health sciences programs







1. Generating Evidence Through Intervention Research Versus Using Evidence in Evidence-Based Practice/Quality Improvement

Bernadette Mazurek Melnyk and Dianne Morrison-Beedy

2. Setting the Stage for Intervention Research and Evidence-Based Quality Improvement: The "So What,a "What Exists,a and "What's Nexta Factors

Bernadette Mazurek Melnyk and Dianne Morrison-Beedy

3. Designing, Conducting, and Evaluating Outcomes of Evidence-Based Quality Improvement Projects

Bernadette Mazurek Melnyk


4. Using Theory to Guide Intervention Research

Julie Fleury and Souraya Sidani

5. Nuts and Bolts of Designing Intervention Studies

Bernadette Mazurek Melnyk, Dianne Morrison-Beedy, and Shirley M. Moore

6. Designing Interventions That Are Sensitive to Culture, Race/Ethnicity, and Gender

Usha Menon

7. Ethical Considerations in Designing Intervention Studies

Dónal P. O'Mathúna

8. Minimizing Threats to Internal Validity

Jacqueline Dunbar-Jacob

9. Minimizing Threats to External Validity

Wanda K. Nicholson

10. Measurement in Intervention Research

Dianne Morrison-Beedy and Bernadette Mazurek Melnyk

11. Biological Measures for Intervention Research

Rita H. Pickler and Cindy Munro


12. Developing the Budget for Intervention Studies

Steven Pease and Barbara Smith

13. Navigating the IRB for Investigators

Amanda A. Hastings, Cheryl L. Byers, and Barry B. Bercu

14. Participant Recruitment and Retention

Dianne Morrison-Beedy and Constance Visovsky

15. Maintaining Fidelity of an Intervention

Sandee McClowry and Sandra Gagnon

16. Study Implementation: An Example Using the Madres Para la Salud (Mothers for Health) Study

Colleen Keller and Barbara Ainsworth

17. Considerations in Conducting Multisite Trials

Peter A. Vanable

18. Considerations in Conducting Interventions in Specialized Settings

18.1. Conducting Interventions in Global Settings

Carol M. Baldwin, Luis Gabriel Cuervo, and Christine Hancock

18.2. Conducting Interventions in Long-Term Care Settings

Debra Parker Oliver and Marlys R. Peck

18.3. Conducting Interventions in Public Health Settings

LaRon E. Nelson and Dianne Morrison-Beedy

18.4. Conducting Interventions in School Settings

Bonnie Gance-Cleveland

18.5. Conducting Interventions in Palliative Care Settings

Kathryn B. Lindstrom

18.6. Conducting Interventions in Acute Care Settings

Cindy Munro

19. Data Management

Sharon M. Lawlor and Kevin E. Kip


20. Analyzing Intervention Studies

Laura A. Szalacha

21. Cost-Effectiveness Analyses for Intervention Studies

Kimberly Arcoleo and Kevin Frick

22. Explaining Intervention Effects

Kimberly Arcoleo


23. Writing Grants That Fund!

Bernadette Mazurek Melnyk and Dianne Morrison-Beedy

24. Submitting a Research Grant Application to the National Institutes of Health: Navigating the Application and Peer Review System

Mindy B. Tinkle and Ann Marie McCarthy

25. Writing Progress and Final Reports

Margaret Roudebush and Shirley M. Moore


26. Disseminating Findings of Intervention Studies

Marion E. Broome

27. Social Media Use in Intervention Research and Dissemination

Linsey N. Grove and Dianne Morrison-Beedy

28. Speeding the Translation of Evidence-Based Interventions Into Real-World Practice Settings

Bernadette Mazurek Melnyk

29. Factors Influencing Successful Uptake of Evidence-Based Interventions in Clinical Practice

Sharon Tucker



First Edition received 2012 First Place AJN Book of the Year Award in Nursing Research!


“This is a resource for success and should be a part of any researcher's library."


--Doody's Medical Reviews (Praise for the First Edition)